Viagra and Impotence

Sildenafil (Viagra), it is intended for impotence treatment (also known as erectile dysfunction). It was the first oral treatment for this purpose.

What reasons of an impotence? How Viagra influences an erection? Whether there are by-effects and interactions of medicines? Learn about them …

The impotence is consecutive inability to support an erection, sufficient for sexual intercourse fulfillment. The impotence can be full inability to reach an erection, incompatible ability to do it, or a tendency to support only short erections. Disease increases with the years: about 5 percent of men at the age from 40 and from 15 to 25 percent of men aged is more senior 65 years of experience of powerlessness.Nevertheless, it not an inevitable part of aging.

Medical workers often use the term “erectile dysfunction” to describe impotences. An impotence and erectile dysfunction, it is necessary to distinguish from other conditions which prevent at sexual intercourse, for example, absence of sexual desire and a problem with ejaculation and an orgasm.

Damage of arteries, smooth muscles and penis nerves can lead to an impotence. One of the widespread reasons of an impotence blood vessels and nervous damages because of a diabetes. Other reasons of an impotence concern low level of testosterone, disease of kidneys, chronic alcoholism, a multiple sclerosis (illness of nervous system), an atherosclerosis (that surgical damage of nerves and blood vessels (for example leads training blood vessels), operations on prostate to gland), and traumas of a penis, a bladder, a basin and a spinal cord.

Some widespread medicines make impotences as a by-effect. Preparations some a high blood pressure concern them, antihistamine preparations, energizers, tranquilizers, suppression of appetite and cimetidine (preparation ulcers). Smoking influences a blood-groove in veins and arteries, and also believe, impotences lead.

Psychological factors, such as stress, anxiety, sense of guilt, depression, a low self-appraisal and the fear of sexual failure connected with an impotence.

If the basic disease leads to an impotence can’t be corrected, or if a problem impotence remain, medicines can help to reach to some men erections sufficient for sexual intercourse, and also to support an erection after penetration.

The penis consists of two chambers named cavernous of bodies which work to length of body. Installation begins with touch and intellectual stimulation. Impulses from a brain and local nerves the reason of muscles of cavernous bodies to relax, allowing blood a leak in and to fill chambers. Blood inflow creates pressure in the cavernous bodies chambers, doing a penis to extend. Installation return when muscles of a penis of the contract, the termination of inflow of blood and causing blood in chambers to follow.

Cyclic guanosine monophosphate (cGMP), alarm molecules in cages, tells smooth muscles in the cavernous bodies to relax, and it allows blood a leak in chambers and to appear in a trap for an erection.

The erection is lost at the cGMP level decrease of cGMP, therefore muscles of a body of contracts cavernous bodies again collapses enzyme (PDE-5), blood flows from chambers the case of the cavernous bodies and an erection no more that.

Sildenafil (Viagra) is oral the agent recently approved FDA the USA for treatment of erectile dysfunctions. Its basic mechanism of action is the inhibition of enzyme PDE-5.The inhibition of this enzyme allows cyclic GMP to remain longer that allows to support an erection. Viagra not an aphrodisiac, it isn’t effective without sexual stimulation. It, basically increases normal physiological erections.

Clinical tests with Viagra use have been spent at patients with vascular diseases, a diabetes, spinal cord damages, the psychogenic reasons, and after radical face downwards surgeries. About 70% -80% of men have informed on quality improvement their erection. More than 50% of patients were able have successful vaginal penetration of use of Viagra.

Viagra orally in an hour to prospective sexual activity, it is desirable next the heart.Absorption Viagra can be reduced on fat food.

Viagra are eliminated the core of system of cytochrome P450 in a liver. Elderly men and men with diseases of a liver or infringement of function of kidneys have reduced possibility to exclude a preparation. Thus, these patients should begin with a low dose (25 mg) to avoid problems with toxicity. Medicines which disturb cytochrome P-450 (for example, erythromycin, cimetidine, and ketoconazole), viagra elimination can reduce also. These other medicines it is desirable to be stopped at Viagra use, or Viagra it is necessary to use with care, since the lowest dose.

Viagra is used separately can cause easy decrease in a blood pressure. But it shouldn’t be used together with nitrates (nitroglycerine, isordil, and others connected with preparation) because of considerable a low blood pressure (hypotonia) which can develop.

By-effects depend on a dose are connected among themselves. Headaches have been noted in 16%, washing of 10%, dyspepsia 7%, and sight infringement (infringement dark blue / green color of discrimination) of 3%.


Warning: Division by zero in /home/xowxzasp/public_html/whitespider.org/wp-includes/comment-template.php on line 1381