Collectively, these results suggest an important opportunity to review and improve the selection of patients undergoing PCI in non-acute, the authors write.* Chris Smith, a cancer research scientist funded by the University of Wales Cardiff Medical Genetics, said: This is the first genetic region identified by genome wide association study shown to influence both survival and response to therapy in patients with advanced colorectal cancer.
In a review of the appropriateness of widespread use of percutaneous coronary intervention , researchers found that more than 500,000 PCI included in the study, almost all acute indications were classified as appropriate, while only about half of PCI performed for non-acute indications could be classified as appropriate, according to a study on the July 6 issue of JAMA.
And ‘in hospitals was important variation in the proportion of inappropriate procedures for non-acute indications. Hospitals in the lowest quartile of PCI had an inadequate rate of 6 % or less, while the rate of inadequate PCI was more than 16 % of hospitals in the top quartile. The data analysis suggests a probability of 80 % more patients with identical clinical features are inappropriate in a hospital PCI randomly selected over the other.
A better understanding of the clinical parameters that occur in PCI and inadequate reduction of variation between hospitals should be the objectives of improving quality.
Of 500 154 procedures classified, 103,245 were ST-segment elevation myocardial infarction, 105,708 for a myocardial infarction without ST segment elevation 146 464 high-risk unstable angina, and 144,737 for acute non-elective indications. Based on the use of criteria for defining the procedures for acute, 355417 PCI were indications of acute and 144,737 were for non-acute indications.8 % of all acute procedures, while high-risk unstable angina consists of 41.