The molecular biology of leukemia has been studied in the past 20 years

The molecular biology of leukemia has been studied in the past 20 years, and we thought we had found most of the common genes for leukemia, comments senior author Craig B. Thompson, director of the Abramson Cancer Center of the University of Pennsylvania here . Now we a significant to show a marked type of mutation for half of the remaining leukemias for which we did not know the cause and between a quarter and one third of leukemia in older patients. The results will be in this week, Cancer Cell.

Other gene-related causes of leukemia breaks and reformations are mentioned in the chromosome translocations.The ease the researchers were able IDH detect mutations in tumor samples, and the ability to identify patients with these mutations due to the presence of increased 2HG gives hope for better detection of AML and suggests that could be blocking the production of 2HG , the ability of the mutated Gene leukemic cells leukemic cells to reverse. ‘If we were in a position to tumors by blocking the production of 2HG are, we might be able to stop the patient leukemia,’says Thompson. Why 2HG production leads leukemia is not yet clear. There does not seem to act as inducing other carcinogenic metabolites that further mutations. One possibility raised in the manuscript is that 2HG accumulation the ability of the ability of differentiated leukemia cells in normal blood cells.

Three years created SNM PET Centre of Excellence a PET Utilization Task Force for tackle specific challenges in. Which Research Working Group, Washington DC area PE Utilization Taskforce met last August in Denver, Colorado development of development of a cost-benefit research workshop. This workshop will is a step in the development of considerable cost and clinical efficacy of research at PET / CT and Molecular imaging comprises in areas concentrated of oncology, cardiology and neurology. An essential component of of the workshop is to cooperation between experts in molecular imaging. Together with the leaders in healthcare research with a view to defining the optimal method and producing a plan to one ore more Molecular imaging comprises effectiveness of research projects – The grant made AHRQ SNM hosting the workshop ‘Comparative Effectiveness in the Molecular Imaging ‘, 21 to 22 Jul , is in the Washington, DC area. The two day workshop information review the current information on of molecular imaging, 100 to 120 health care costs and as clinical and cost-effectiveness research can serve as an method of addressing of these questions for managing the the treatment and cancer patient management in today healthcare.

Establish clinical and cost of research for molecular imaging being a top priority for Graham and one of his most important goals Date assuming office as a SNM the President in June 2009.