Smoking cessation drugs is not linked to an increased risk of self harm or depression

They require further investigation of the effects of varenicline on the risk of suicide in databases and secondary analysis of all other reports of adverse events in clinical trials.There is substantial evidence that popular drug varenicline for smoking cessation increases the risk of self harm or depression than other smoking cessation products, according to new research published on bmj.com.

The authors note that even if you did not find strong evidence of an increased risk of self harm associated with varenicline, ‘the limited power of the study means that we can not exclude either a half or double the risk.’

After adjustment for confounders, there was no clear evidence of an increased risk of self harm, suicidal thoughts or depression associated with both varenicline and bupropion.

Participants were prescribed for both nicotine replacement products , varenicline , or bupropion .

Varenicline is a product of the recently introduced smoking cessation of proven efficacy, but there were concerns that may increase the risk of suicidal behavior and suicide. Despite warnings about possible increased risks issued by regulatory authorities worldwide, varenicline continues to be widely used.

This school intervention for four years in Ann Arbor, Michigan, is designed to promote healthier lifestyle choices and shows that programs like this could have long-term impact on obesity and health risks, said Elizabeth A. Jackson, MD, MPH, co-author of the study and assistant professor of internal medicine at the University of Michigan. These changes can have lasting benefits in terms of reduction of diabetes and cardiovascular diseases such as age of the students.

To provide further evidence, a team of researchers at the University of Bristol and the UK Medicines and Health Products Regulatory Agency has compared the risk of self harm in people taking varenicline risk of self harm associated with other therapies bupropion smoking cessation and nicotine replacement .