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Mifepristone and Misoprostol. These two drugs are anti-estrogen and anti-progesterone hormones. They successfully terminate the pregnancy within the first trimester by disturbing the form of uterine and destroying its inner lining. What are the precautions I must take through the entire course? There are several important precautions that an end consumer must take into account before starting a course. * Do not hide anything from your doctor, when you have any chronic diseases, blood circulation pressure then kindly share it with a doctor. * Keep these drugs away from children and additional family members.