The data de novo steroidogenesis implied as the primary driver of the tissue androgen synthesis in this model. The study underlines the fact that it is very difficult to actually tissue tissue androgen levels, even with effective secondary manipulations. Lowering tissue androgens rather than vice versa, but only slowed the growth of tumors, supporting the idea that in this model, there are other factors the progression on androgens..
However, there was evidence that prostate cancer is also capable of synthesizing androgens de novo from cholesterol, and determining which way should the primary target in human disease is unclear. This study used mice models, this model there judged not available for conversion androgens by the tumor, and whether estrogens inhibit tumoral androgen levels. If so, then the design of future must consider must consider the contribution the de novo steroidogenesis does in the tumor progression.. There is a strong tendency in the community that castration-resistant prostate cancer androgens into testosterone into testosterone and dihydrotestosterone to drive tumor growth advantage.Taser is a brand name for type carried out electrical weapons A total two clearly defined metal probes produce 19 electric impulses per second triggered.