New insight into the causes of anorexia

Adolescence is a period of transition, when individuals must learn to balance the immediate needs and long-term goals to achieve independence, said Kaye. For these people, learn to deal with mixed messages and social pressures that can be overwhelming, which exacerbates the underlying traits of anxiety and the desire to complete successfully. Although anorexia is characterized as an eating disorder, it remains unknown whether it is primarily a disorder of appetite, or if a change of appetite is secondary to other problems such as anxiety or obsessive concern with weight gain. When people are malnourished and emaciated with disease spread and serious changes in the brain and other organs. Since it is unclear whether these changes are the cause of the result of significant weight loss, people who have recovered from anorexia were studied. While about 50 percent to 70 percent of people eventually recover a significant %age of patients develop a chronic disease or dying from anorexia from the number one cause of death in psychiatric illness.

This leads to a reduction in the number of new neurons and defective maturation of these neurons. Johnson.

A region of the brain is the anterior insula, which is extremely important for interoceptive, or self-consciousness of the body’s internal signals. In addition to an inability to adequately respond to hunger signals, the symptoms of anorexia, such as distorted body image and low motivation to change may be related to interoceptive awareness disturbed.

Personality and infant temperament may increase the vulnerability of an individual to develop anorexia. Predisposing factors, some believed to be hereditary, such as perfectionism, anxiety, or obsessive-compulsive tendencies may precede the onset of an eating disorder. These characteristics are increased during adolescence due to many factors such as hormonal changes, stress and culture.

A better understanding of the basic neurobiology of how behavior is encoded in the brain and contributes to anorexia can lead to more effective treatment, the researchers said.

New imaging technology provides an overview of the abnormalities in brain circuits of patients with anorexia nervosa , which may help to confuse the symptoms in people with eating disorders. In a review article published online in Nature Reviews Neuroscience, Walter Kaye, MD, professor of psychiatry and director of the eating disorders program at the University of California, San Diego and colleagues describe a problem in some neurons in the brain circuits that may contribute to explain why people develop anorexia in the first place, and behaviors as the relentless pursuit of speed and weight loss.

Kaye noted that the traits of temperament and personality that can create a vulnerability to develop anorexia may also have a positive aspect. These features include the attention to detail, concern for the consequences, and a drive to achieve and succeed. It ‘s my clinical experience that many people who recover from anorexia to succeed in life, he said.

Anorexia is very complicated, and there must be a paradigm shift in the understanding of its underlying causes, said Kaye. We’re just beginning to understand how the brain works in people with this disorder.

Currently, we have very effective way to treat people with anorexia, said Kaye.

As a result, many patients with the disease remain ill for years and eventually die of this disease, that the highest mortality rate of any psychiatric disorder.