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The new method presented by Kyohei Terao from Kyoto University, and co-workers from The University of Tokyo, uses micron-sized hooks managed by lasers to catch and straighten a DNA strand with excellent precision and care. ‘Whenever a DNA molecule is manipulated and straightened by microhooks and bobbins, the gene location can be determined easily with high-spatial resolution,’ says Terao. The team used optical tweezers – tightly focused laser beams – to control the Z-shaped micro hook and grab an individual DNA ‘thread’. The hook is barbed like an arrow, therefore the thread can’t get away. When caught on the hook, the DNA can be accurately shifted around by refocusing the lasers to brand-new positions. But just like thread in a sewing machine, an extended DNA chain can be unwieldy – so the experts built micro ‘bobbins’ to wind the chain around.