Imaging of diseased cells to be helped sleeping Trojans

The study ‘Trojan Horse Sleeping Beauty’ that transports metal ions in cells, localises in nucleoli, and has the potential to be published bimodal fluorescence / PET chemical communication in the advanced section of the article. Published by the Royal Society of Chemistry, this is the major revision for the weekly publication of important developments in the field of chemical sciences.‘There are other possibilities for use in radiation therapy as a form of metal that covers not only enters the cells, but also localizes to the nucleolus. In principle, the concept could also be used to improve the delivery of a wide range of drugs and imaging agents into cells or the body. ‘

Medical imaging often requires the obtaining of artificial materials such as metal ions into cells, a process that is a major challenge in a wide range of biomedical disciplines. One technique currently used is called the ‘Trojan horse’ that is connected to the drug or imaging agent to something naturally absorbed by the cells.

The research was led by Dr Mike Coogan, Senior Lecturer in chemical synthesis, with the first author of the document, Flora Thorp-Greenwood.

My dream is to get going parallel Preclinical these high-risk individuals as well as the general population. We want to launch a period of research for prevention, where the terrain at high estimated pre-symptomatic treatment of a strict and timely manner randomized clinical trials, said Reiman.

Dr Coogan said: ‘The process of Trojan horse is going to sleep fast, and the ship is capable of transporting metals have isotopes that emit positrons, so has the potential for use in bimodal fluorescence and PET imaging agents combined for these types of imaging are known.

but rare, so this is a significant development in the area.