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All statements in this press release about ChemoCentryx expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts are forward-looking statements. These statements are often but not always, made through the use of words or phrases such as may, believe, expect, anticipate, estimate, intend, predict, seek, potential, continue, plan should, could and would or the negative of these terms or other similar terms. Forward-looking statements are not a guarantee of performance. They involve known and unknown risks, uncertainties and assumptions that could cause actual results, levels of activity, performance or achievements to differ materially from results, levels of activity, performance or achievements expressed or implied by such statements forward-looking statements. Some of the risks, uncertainties and assumptions that could cause actual results to differ materially from estimates or projections contained in forward-looking statements include, but are not limited to: (i), the initiation timing, progress and results of preclinical studies and ChemoCentryx clinical trials, (ii) ChemoCentryx ability to advance product candidates in clinical trials, (iii) GSK’s exercise of its license options, (iv) the commercialization of product candidates ChemoCentryx, (v) the implementation of business model of ChemoCentryx strategic plans for its business, product candidates and technology, (vi) ChemoCentryx ability to maintain and establish collaborations or obtain additional government grants for funding, (vii) ChemoCentryx estimates of its expenses, future revenues, requirements capital and the need for additional financing, (viii) the timing or likelihood of regulatory filings and approvals, (ix) the availability of corporate partners, (x) the scope of protection ChemoCentryx is able to establish and maintain Intellectual property rights and technology related products, (xi) the impact of competitive products and technological changes, (xii) the availability of capital and the cost of capital (xiii) ChemoCentryx financial performance, (xiv) developments relating to ChemoCentryx competitors and other vagaries of the biotechnology industry and (xv) other risks.

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You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement and ChemoCentryx assumes no obligation to revise or update this press release to reflect events or circumstances after the date hereof. This caution is made under the safe harbor provisions of Section 21E of the Law of Private Securities Litigation Reform Act of 1995.

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Under the terms of the collaboration, ChemoCentryx will receive a commission to exercise the option of 35 million and may have other regulatory milestone payments. After the successful development and commercialization of one of the candidate compounds, ChemoCentryx will also receive double-digit royalties on sales of products with the ability to raise taxes by the co-funding development through Phase III clinical trials studies and co- promotion with medical specialists in North America. GSK now assume responsibility for the further development of CCX282-B in patients with moderate to severe Crohn’s disease. Potential ulcerative colitis studies also considered for this product candidate.

The chemokine system is a network of secreted chemokine molecules, or ligands, and cell surface receptors that regulates inflammation. Working with partners like GSK has been challenging and we look forward to advancing CCX282-B as well as complementary programs that make up our alliance. Seventeen compounds were measured in meconium samples using methods that detect very low levels of chemicals. Crohn’s disease is a chronic disease, patients continue therapy by the time of diagnosis during life, complementary therapies such as depth or overlapping use persist in an attempt to reduce symptoms.