Genes play bigger role in heart attacks to strokes: study

People are much more likely to inherit a predisposition for a heart attack and stroke, according to a study reported in the journal Circulation: Cardiovascular Genetics, an American Heart Association journal. First, physicians and to predict the likelihood of a healthy person of a heart attack or stroke needs refining, he said. Currently, most of the risk models lump a patient’s family history of heart attack and stroke together. Maybe we should model a family history of stroke and stroke separately in the future.

In cardiac patients, 30 % have a parent who had had a heart attack, 21 % had at least one brother who had suffered a heart attack. Seven % have two or more brothers who had heart attacks and 5 per cent have both parents of a heart attack.

Among patients with stroke or transient ischemic attack , 21 % have a parent who has had a stroke, and 2 % had two parents per cent of stroke. Eight had at least one sibling with a stroke and 14 % had at least two siblings of stroke.

The risk of an acute cardiac event was six times greater if both parents had suffered a heart attack a year and a half times higher if a parent had a heart attack. However, the likelihood of stroke has not changed much with the results of the race of parents’ history.The, if confirmed by further studies, have two important consequences, Rothwell said.

The men who participated in moderate to heavy activities were 63 % less likely to have a stroke than people without physical activity. The baseline risk of ischemic stroke in five years in the whole group was 4.7 %, and among those with no activity was 4 , 6 per cent.

We found that the association between a parent having a heart attack and you have a heart attack was much stronger than the association between the parent has a stroke and you have a stroke, said lead author said Peter M.D., professor of clinical neurology at the University of Oxford in England. This suggests that susceptibility to stroke is less strong hereditary predisposition to the crisis center.

OXVASC, is known as the study began in 2002 to study stroke, heart attacks and other acute vascular events in one part of the county of Oxfordshire, serving more than 91,000 people to a hospital. Previous analysis in the same population conducted by Amitava Banerjee lead author MPH PhD, has highlighted the particular importance of family history of mother-daughter in both heart attacks and strokes. A family history of heart attacks and family history of stroke has been little studied in the same population, said Banerjee.

The risk of developing acute heart problems siblings was similar to those of a heart attack or stroke.

The new data also indicated that the same criteria to predict medical events overestimate the risk of stroke, he added. The knowledge of genetic factors in the race behind shifts in coronary artery disease, said Rothwell. The discovery that genes play a much smaller race could mean that genetic studies of race can not be critical of the field, he added.

The researchers used data from 906 patients suffering from acute heart disease and 1015 patients who have suffered acute cerebral events.

Among the study’s conclusions: