Extreme form of morning sickness during pregnancy may be genetic

The findings are published online in the Journal of Obstetrics and Gynecology.About 60,000 pregnant women are hospitalized every year because of hyperemesis gravidarum , an extreme form of nausea and vomiting, which endangers their lives and often reluctantly forced to terminate the pregnancy.

This study was funded by the Hyperemesis Education and Research Foundation, the intramural research program at the National Institute of Child Health and Human Development, National Institutes of Health, and the U. Department of Health and Social Services. Other researchers in this study were Yafeng Zhang and Rita M. Cantor, UCLA, Thomas M. Goodwin and Patrick Mullin of USC, Kimber MacGibbon Education and Research Foundation of hyperemesis: Roberto Romero, National Institute of Child Health and Human Development.

And women with sisters, mothers and grandmothers on both sides of the family who had a great pregnancy, the risk of HG can be increased, according to a new study by researchers at UCLA and the University of Southern California.

Their analysis showed that the addition of behavioral therapy, medication management of migraine significantly increased participants ‘confidence’ in their ability to self-manage migraine, compared to a migraine medication alone. Managing the behavior of participants has increased even believe ‘that migraine may be influenced by their behavior and a decrease in the belief that migraine is primarily influenced by chance or fate.

The researchers traced the history of women in the family of father and mother with HG and have found that not only the condition may be genetic, but that women with sisters who had HG may be a risk more than 17 times to experience the debilitating condition too.

Previous studies have used hospitalization and other medical records to examine the prevalence of this disease among groups of mysterious people. A look at drugs nausea of ​​pregnancy in identical twins than fraternal twins, and another focused on the mother-grandson of recurrence. Overall, previous studies have suggested that genetics are involved.

The researchers found that women with HG were more than five times more likely than controls to report having a sister with nausea and vomiting or HG. Among the sisters who had undergone HG – serious illness and sisters excluded morning only – study participants with HG was 17.3 times more likely to also have the condition.

‘Because the incidence of hyperemesis gravidarum is the most commonly reported was 0.

5 per cent in the population, and sisters of cases as familial risk increased 18 times more of HG compared with controls, this study provides strong evidence of a genetic component of nausea and vomiting during pregnancy, ‘the authors conclude.