A previous study published earlier this year in June UCSF Chan, SCD, and colleagues at the Harvard School of Public Health, has shown that physical activity after diagnosis could reduce disease-related mortality in a distinct population of men with prostate cancer. The new study complements this finding, as was the first to focus on the effects of physical activity after diagnosis on early indications of disease progression such as increased rates of prostate specific antigen blood .Co-authors of the study are Lynda Voigt, associate professor of epidemiology, and Barbara McKnight, professor of biostatistics. The research was funded by grants from the National Cancer Institute.
A study of 1,455 American men diagnosed with prostate cancer at an early stage has found a link between brisk walking and reduced risk of progression of prostate cancer, according to scientists at the University of California, San Francisco and the Harvard School of Public Health.
Vigorous exercise and brisk walking have been consistently shown to have significant benefits for cardiovascular health, diabetes and many other diseases. Previous studies have also shown the benefits of regular physical activity for the results of the disease of breast cancer and colon cancer, but it is one of the first studies to show a benefit for men with prostate cancer.
This work was funded by the Department of Defense, the Prostate Cancer Foundation, Abbott Labs, and a National Institutes of Health training grant.
The scientists found that men who walked briskly – at least three mph – for at least three hours a week after diagnosis were nearly 60 % less likely to develop biochemical markers of cancer recurrence or need a second course of treatment for prostate cancer.
The ‘Physical activity after diagnosis and the risk of prostate cancer progression: data from the prostate cancer Strategic Research Endeavor Urology’ article is written by Erin L. Kenfield, J. Meir Stampfer, Alan Paciorek, Peter R. Carroll and Mr. Chan in June
‘Our results suggest that it is important to engage in exercise that gets your heart beat a little, ” he advised.
A particular strength of this study is the emphasis on early recurrence of prostate cancer, which occurs before men may experience symptoms of painful metastatic prostate cancer, a common cause for men to reduce their normal physical activity . In addition, researchers have reported that the benefits of physical activity was independent of age at diagnosis, type of treatment and clinical features of disease at diagnosis.
‘Our work suggests that intense physical activity or brisk walking can have an advantage in the early stages of the disease,’ said Chan, Professor Steven Burd, Safeway and Christine emeritus at UCSF and senior author of both studies.