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Enhanced when piece measures 54 weeks and a mean Macugen injections of 7, the mean the best visual acuity 14 letter to baseline, Other the center thick decrease 205 m and the average macular volumes reduce 2, mean BCVA Related improvements 0.3 mg of 0.3 mg and 1 mg of doses. In week 1, 47 percent of eyes of did gained less than 10 letters and 18 percent donated 15 or more letters. Have in week 30 won 50 percent of eyes 15 or more letters These enhancements are maintaining at 54 weeks. About MacugenMacugen, a selective inhibitor of VEGF-165, being in the U.S. For the treatment of of neovascular age -related macular degeneration and be licensed each in a 0.3 -mg dose again administration six weeks by intravitreal injection. Macugen is a pegylated anti-VEGF aptamers vascular endothelial growth factor vascular endothelial growth factor . VEGF is a protein Inch neovascular AMD. Decisive role in angiogenesis and increased permeability , two pathological processes that contributing does loss of vision associated with neovascular AMD.