Tell your doctor if you are pregnant or plan to become pregnant. During pregnancy, the drug should be used only if clearly needed toradol 10 mg . It is not recommended for use in the first and last trimesters of pregnancy because of possible damage to unborn child and interference with the delivery of work / normal. Discuss the risks and benefits with your physician before using this medicine. Before breastfeeding passes into breast milk in very small amounts and may have adverse effects on the infant. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
AMT was founded in 1998 and headquartered in Amsterdam, is a leading developer of human gene therapy based. Using AAV as a delivery vehicle of choice for therapeutic genes, the company was able to design and validate what is probably the first stable and scalable platform AAV production. This platform is safe and effective property offers a unique capability of production that can be applied to a large number of rare (orphan), which are caused by a defective gene. Currently, AMT has a product portfolio with several products based on AAV gene therapy in LPLD, Hemophilia B, DMD, acute intermittent porphyria, and Parkinson’s disease in different stages of research or development.
Currently, frequent intravenous administration of recombinant factor IX is required to stop or prevent bleeding. Protein replacement therapy is expensive, cumbersome, and not completely prevent bleeding.
Hemophilia B is characterized by severe episodes of bleeding externally and internally, resulting in significant morbidity. The episodes cause long term damage, such as joints, and can be fatal if they occur in the brain. The failure of blood clotting in hemophilia B is caused by the lack of factor IX clotting function due to mutations in the gene encoding this protein. The factor IX gene is located on chromosome X. This is an X-linked recessive trait, which is why only the males are usually affected.