Abnormal activation of cell death pathways can lead to inflammatory skin diseases Inflammatory skin diseases such as for example psoriasis may derive from abnormal activation of cell loss of life pathways previously thought to suppress inflammation, a surprise finding that could help to build up new ways of treating these diseases. Mr James Rickard, Associate Professor John Silke and co-workers from the Walter and Eliza Hall Institute made the discovery while investigating how cell death pathways are associated with inflammatory disease development. The analysis was released today in the journal eLife.All authors attest to the completeness and precision of the data presented. Patients admitted to the ICU with an expected duration of mechanical ventilation of more than 48 hours or an anticipated ICU stay of more than 72 hours were eligible. Eligibility was assessed by physicians responsible for patient care in each unit. Pregnant patients and sufferers with documented or presumed allergy to any element of the antimicrobial study regimens were excluded. The study protocol was approved by the institutional review board at each participating hospital. After reviewing the process, the boards waived the necessity for informed consent.